Chagas Disease

National Organization for Rare Disorders, Inc.

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It is possible that the main title of the report Chagas Disease is not the name you expected.

Disorder Subdivisions

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General Discussion

Chagas Disease is a tropical infectious disease caused by the parasite Trypanosoma cruzi. It is transmitted by the bite of one of several species of blood-sucking insects or by blood transfusion. Acute Chagas Disease usually affects children and typically presents as the mild phase of the disease. However, this is generally followed by a long period of low level, parasitic infection (parasitemia). Many years later, about 10 to 30 percent of people with Chagas Disease develop the more severe symptoms associated with "chronic" Chagas Disease. The heart and digestive systems are most frequently involved in this phase of the disease. The most common features of late chronic Chagas Disease include abnormal enlargement of the esophagus (megaesophagus) and colon (megacolon), and congestive heart failure. Chagas Disease occurs primarily in Central and South America.

Supporting Organizations

Centers for Disease Control and Prevention

1600 Clifton Road NE
Atlanta, GA 30333
Tel: (404)639-3534
Tel: (800)232-4636

Genetic and Rare Diseases (GARD) Information Center

PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311

NIH/National Institute of Allergy and Infectious Diseases

NIAID Office of Communications and Government Relations
5601 Fishers Lane, MSC 9806
Bethesda, MD 20892-9806
Tel: (301)496-5717
Fax: (301)402-3573
Tel: (866)284-4107

National Dysautonomia Research Foundation

PO Box 301
Red Wing, MN 55066-0102
Tel: (651)327-0367

World Health Organization (WHO)

Avenue Appia 20
Geneva 27, 1211
Tel: 41227912111
Fax: 41227913111

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.

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Last Updated:  5/11/2009
Copyright  2009 National Organization for Rare Disorders, Inc.